Neoreviews
HOME HELP CONTACT US SUBSCRIPTIONS CME ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Take the CME quiz:
 Vol. 10 No. 12, December 2009
Right arrow E-Letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-Letters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Google Scholar
Right arrow Articles by Taylor, S. N.
Right arrow Articles by Wagner, C. L.
PubMed
Right arrow Articles by Taylor, S. N.
Right arrow Articles by Wagner, C. L.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Facebook   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

NeoReviews Vol.10 No.12 2009 e590
© 2009 American Academy of Pediatrics

Vitamin D Needs of Preterm Infants

Sarah N. Taylor, MD*
Bruce W. Hollis, PhD*
Carol L. Wagner, MD*

* Department of Pediatrics, Medical University of South Carolina, Charleston, SC

The 2008 revised American Academy of Pediatrics (AAP) recommendation for 400 IU/day vitamin D intake makes progress toward achieving infant vitamin D sufficiency in the United States. Further study, however, is needed both to define vitamin D sufficiency for preterm infants based on markers of vitamin D biologic function and to develop supplementation strategies to ensure adequate vitamin D intake and, thus, vitamin D sufficiency in this at-risk population. In this review, we highlight some of the issues surrounding vitamin D status of the neonate and the particular risks for the preterm infant. We review the evidence regarding the impact of vitamin D deficiency in this population and the safety and efficacy of vitamin D supplementation. Based on previous study in preterm infants, the current AAP guidelines to achieve serum 25-hydroxyvitamin D [25(OH)D] status of at least 50 nmol/L and to receive at least 400 IU/day are safe and possibly adequate. Because of the nutritional difficulties in achieving consistent delivery of 400 IU/day of vitamin D in the preterm infant, it is imperative to devise strategies for close monitoring of each preterm infant's vitamin D status and consider oral vitamin D supplementation as an important adjunct to dietary sources and multivitamin preparations.

Abbreviations: AAP: American Academy of Pediatrics • CI: confidence interval • DBP: vitamin D-binding protein • DEXA: dual-energy x-ray absorptiometry • ESPGAN: European Society for Pediatric Gastroenterology and Nutrition • 1,25(OH)2D: 1,25-dihydroxyvitamin D • OR: odds ratio • PTH: parathyroid hormone • 25(OH)D: 25-hydroxyvitamin D • VLBW: very low birthweight


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?




HOME HELP CONTACT US SUBSCRIPTIONS CME ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2009 by the American Academy of Pediatrics.