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Vol. 8 No. 11, November 2007
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NeoReviews Vol.8 No.11 2007 e485
© 2007 American Academy of Pediatrics

Myths and Dogmas in Neonatal Gastroenterology and Nutrition

Josef Neu, MD*

* Professor of Pediatrics, University of Florida, Gainesville, Fla

Widespread clinical care practices in neonatology are based on tradition rather than a solid scientific foundation. For example, the concept that parenteral nutrition is totally adequate in neonates and that enteral nutrition can be withheld for prolonged periods may be incorrect; several adverse consequences are associated with a lack of enteral nutrients. The interaction between the intestinal microbiome and the innate and adaptive immune system suggest that general administration of broad-spectrum antibiotics to very low-birthweight infants shortly after birth may be associated with both short- and long-term potential adverse effects. Finally, factors other than food intake may be related to the development of the metabolic syndrome, suggesting that avoidance of "aggressive" nourishment shortly after birth and "catch-up" growth may not be appropriate.


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