|
|
|||||||||
|
|
NeoReviews Vol.9 No.10 2008 e447
© 2008 American Academy of Pediatrics

* Professor of Pediatrics, Division of Neonatology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah
Professor of Pediatrics, Medicine, and Neurobiology & Anatomy, Division of Neonatology, Department of Pediatrics, University of Utah School of Medicine, Salk Lake City, Utah
A variety of insults can contribute to lung inflammation in the neonatal period. Many of these insults exert their effects through activation or suppression of critical transcription factor pathways. The effect of these pathways on gene transcription/protein translation has a direct impact on lung development, labor induction and the intra-amniotic milieu, and postnatal lung inflammation.
Abbreviations: BMP: bone morphogenetic protein BPD: bronchopulmonary dysplasia FGF: fibroblast growth factor I kappa B: inhibitor kappa B IL: interleukin iNOS: inducible nitric oxide synthase LPS: lipopolysaccharide NF-kappa B: nuclear factor-kappa B PGI: prostaglandin PPAR: peroxisome proliferator-activated receptor PTHrP: parathyroid hormone-related protein RDS: respiratory distress syndrome RXR: retinoic acid receptor Shh: sonic hedgehog TGF: transforming growth factor TLR: toll-like receptor TNF: tumor necrosis factor
![]()
CiteULike
Connotea
Del.icio.us
Digg
Facebook
Reddit
Technorati
Twitter What's this?
| HOME | HELP | CONTACT US | SUBSCRIPTIONS | CME | ARCHIVE | SEARCH | TABLE OF CONTENTS |