Neoreviews
HOME HELP CONTACT US SUBSCRIPTIONS CME ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Take the CME quiz:
 Vol. 9 No. 3, March 2008
Right arrow E-Letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-Letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Google Scholar
Right arrow Articles by Manco-Johnson, M. J.
PubMed
Right arrow Articles by Manco-Johnson, M. J.

NeoReviews Vol.9 No.3 2008 e119
© 2008 American Academy of Pediatrics

Hemostasis in the Neonate

Marilyn J. Manco-Johnson, MD*

* Professor of Pediatrics, University of Colorado, Denver, and the Children's Hospital, Denver, Colo

The coagulation system is finely tuned to arrest bleeding at the site of vascular injury and quickly remove clots that obstruct blood flow. In the fetus, components of the coagulation system show unique developmentally regulated patterns and times for maturation to normal adult protein quantities and functions. In addition, several coagulation proteins contribute to cellular proliferation and differentiation uniquely during fetal life. In spite of this, results of most screening tests of hemostasis vary modestly from adult normal values in the healthy term infant, and both hemorrhage and thrombosis are rare in the well infant.






HOME HELP CONTACT US SUBSCRIPTIONS CME ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2008 by the American Academy of Pediatrics.