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NeoReviews Vol.7 No.11 2006 e567
© 2006 American Academy of Pediatrics

Historical Perspectives

Perinatal Profiles: William Little and Cerebral Palsy

The first 20% of the full text of this article appears below.

William John Little (1810–1894), an orthopedic surgeon in England, first described the condition later named cerebral palsy (CP) in a series of lectures he gave to medical students between 1843 and 1844. Having suffered from bilateral clubfoot (residual of poliomyelitis), Little had personal reasons to study and treat children’s deformities. He had helped found London’s Royal Orthopedic Hospital, where he gave these seminal talks, (1) and in 1853, published them in a monograph. (2)

Today, about 163 years since Little’s classic description, an intellectual renaissance has occurred in the study of CP. A new definition and classification of CP have been proposed; (3) newer neuroimaging techniques . . . [Full Text of this Article]

Tonse N.K. Raju, MD, DCH^*

^* Medical Officer/Program Scientist, Pregnancy and Perinatology Branch, Center for Developmental Biology and Perinatal Medicine, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Md