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NeoReviews Vol.7 No.2 2006 e67
© 2006 American Academy of Pediatrics

Historical Perspectives

Cured by the Blood: The Story of the First Neonatal Blood Transfusion

The first 20% of the full text of this article appears below.


   Case Report
 
On March 4, 1908, a baby girl was born to healthy parents at a New York Hospital. She weighed 8 lb 12 oz. Other than forceps marks over her cheeks, she appeared healthy.

At 12 hours of age, she developed a hematoma over her tongue. That afternoon, she developed a fever to 102.2°F (39°C). She looked pale and restless and cried continuously. A subcutaneous hematoma was noted behind the left ear, extending down to her neck over the next 36 hours. She passed dark-colored meconium stools, strongly positive for blood. "Intestinal infection" was diagnosed, and she was treated with 30 minims of castor oil and two grains of calcium lactate. She deteriorated over the next 3 days, and appeared "hopeless" on the fourth day. Blood oozed continuously from her nose. Her skin was waxen white, mucous membranes were colorless, and pulse was feeble.

It was clear that the child needed a blood transfusion, but this had never been tried in a newborn. The doctors considered giving her a "direct transfusion" and asked her father to be the donor. He agreed. Surgeons . . . [Full Text of this Article]

Tonse N. K. Raju, MD, DCH*

* Pregnancy and Perinatology Branch, Center for Developmental Biology and Perinatal Medicine, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Md






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