Neoreviews
HOME HELP CONTACT US SUBSCRIPTIONS CME ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-Letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Conti, A.
Right arrow Articles by Richardson, M. W.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Conti, A.
Right arrow Articles by Richardson, M. W.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Facebook   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

NeoReviews Vol.9 No.5 2008 e223
© 2008 American Academy of Pediatrics

Index of Suspicion in the Nursery

The first 20% of the full text of this article appears below.


   Case Presentation
 
One day after a "routine" circumcision, an otherwise healthy 3-day-old term neonate presents with swelling, ecchymosis, and oozing from the circumcision site. There are no petechiae or other bruises. Pregnancy and delivery had been uncomplicated. His vital signs and growth parameters are normal. Results of his neurologic examination are normal, and he has no skeletal abnormalities or dysmorphic features. He is the third of three male children born to a nonconsanguineous couple. The two older brothers had normal perinatal courses, including uncomplicated circumcisions. There is no family history of hemophilia.

Laboratory work reveals a platelet count of 9.0x103/mcL (9.0x109/L), white blood cell count of 15.0x103/mcL (15.0x109/L), hemoglobin of 17.6 g/dL (176 g/L), and hematocrit of 45.8% (0.458). Review of the blood smear shows no platelet clumps. Ultrasonography of the head shows no intraventricular hemorrhage. The mother has no history of immune thrombocytopenia (ITP), and her platelet count is normal. A platelet transfusion is ordered. One hour after the transfusion, a platelet count is 18.0x103/mcL (18.0x109/L). Four hours later, the platelet count is 10.0x103/mcL (10.0x109/L). Further evaluation of the parents yields the diagnosis.


   Case Discussion
 
The differential diagnosis of severe neonatal thrombocytopenia can be categorized broadly into disorders of increased platelet consumption or decreased production (Table). Included in these categories are congenital viral infection, sepsis, perinatal asphyxia, placental . . . [Full Text of this Article]

Amanda Conti, MD
W. Benjamin Rothwell, MD
Satkiran S. Grewal, MD
Matthew W. Richardson, MD

Baystate Children's Hospital, Springfield, Mass


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?




HOME HELP CONTACT US SUBSCRIPTIONS CME ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2008 by the American Academy of Pediatrics.