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Articles: Robin K. Ohls Transfusions in the Preterm Infant Neoreviews 2007; 8: e377-e386 [Abstract] [Full text] [PDF]

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NPO for blood transfusions

richard inwood   (6 September 2007)

Response to Dr Inwood

Robin Ohls   (6 September 2007)

NPO for blood transfusions 6 September 2007
richard inwood, neonatologist NBIMC, newark, nj Send letter to journal: Re: NPO for blood transfusions rinwood47{at}yahoo.com richard inwood	our group has seen NEC following PRBC transfusion - we now hold feedings for 9 hours - is this rational? do other groups do something like this? Conflict of Interest: None declared Response from Dr Ohls : I have heard other neonatologists raise concerns that the incidence of NEC is increased following red cell transfusions.  There is no published evidence I know of to support this observation.  In general, because of concerns over possible contamination and infection, blood banks prefer that red cell transfusions be completed within 4 hours of removing the blood from refrigerated storage.  For preterm infants in whom volume overload is a possibility, red cell transfusions can be divided into 2 aliquots which can be given over 3 to 4 hours each.
Response to Dr Inwood 6 September 2007
Robin Ohls, neonatologist University of new mexico Send letter to journal: Re: Response to Dr Inwood ROhls{at}salud.unm.edu Robin Ohls	I have heard other neonatologists raise concerns that the incidence of NEC is increased following red cell transfusions.  There is no published evidence I know of to support this observation.  In general, because of concerns over possible contamination and infection, blood banks prefer that red cell transfusions be completed within 4 hours of removing the blood from refrigerated storage.  For preterm infants in whom volume overload is a possibility, red cell transfusions can be divided into 2 aliquots which can be given over 3 to 4 hours each. Conflict of Interest: None declared