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- 1,25OH2D,
- 1α-25-dihydroxycholecalciferol
- 25OHD,
- 25-hydroxyvitam D
- AAP,
- American Academy of Pediatrics
- NIH,
- National Institutes of Health
- PTH,
- parathyroid hormone
Abstract
Since 2008, the American Academy of Pediatrics (AAP) has published three documents related to vitamin D requirements of term and preterm infants. The need for developing and updating such guidelines emphasizes the importance of vitamin D not only as an essential element of bone health but also as a nutrient and prohormone that plays an increasingly recognized role in many other organ systems. In this review, we describe: (1) the main circulating metabolites of vitamin D; (2) the significance of their respective blood concentrations during the assessment of vitamin D status; and (3) the factors that influence vitamin D status at birth and the risk factors for neonatal vitamin D deficiency. In a separate article, we discuss the evidence for current vitamin D dietary recommendations in term neonates and delineate the role of vitamin D deficiency in the pathogenesis of osteopenia of prematurity.
- Copyright © 2014 by the American Academy of Pediatrics
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