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American Academy of Pediatrics
Article

Diabetes Mellitus in Pregnancy

Desmond M. Sutton, Christina S. Han and Erika F. Werner
NeoReviews January 2017, 18 (1) e33-e43; DOI: https://doi.org/10.1542/neo.18-1-e33
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Desmond M. Sutton
*Department of Obstetrics and Gynecology, Women and Infants Hospital of Brown University, Providence, RI
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Christina S. Han
†Center for Fetal Medicine and Women’s Ultrasound, and University of California at Los Angeles, Los Angeles, CA
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Erika F. Werner
*Department of Obstetrics and Gynecology, Women and Infants Hospital of Brown University, Providence, RI
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  • Abbreviations:
    ACOG,
    American College of Obstetricians and Gynecologists
    BMI,
    body mass index
    DKA,
    diabetic ketoacidosis
    DM,
    diabetes mellitus
    FGR,
    fetal growth restriction
    GDM,
    gestational diabetes mellitus
    IUFD,
    intrauterine fetal demise
    T1DM,
    type 1 diabetes mellitus
    T2DM,
    type 2 diabetes mellitus
  • Abstract

    Gestational and pregestational diabetes make up the most common maternal metabolic disorder of pregnancy. Suboptimal control of blood glucose has the potential for serious maternal and neonatal adverse effects. Neonates of diabetic mothers are at risk for congenital malformations, perinatal mortality, preeclampsia, preterm birth, increased birthweight, neonatal hypoglycemia and respiratory distress. The nature and severity of risks depend on the timing and duration of hyperglycemia. Through glycemic control and proper prenatal care, many of these risks can be mitigated. Pediatric providers must be sensitive to the association between a newborn’s risk and the mother’s level of glycemic control, often linked to her adherence to prenatal care.

    • Copyright © 2017 by the American Academy of Pediatrics

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    NeoReviews
    Vol. 18, Issue 1
    1 Jan 2017
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    Diabetes Mellitus in Pregnancy
    Desmond M. Sutton, Christina S. Han, Erika F. Werner
    NeoReviews Jan 2017, 18 (1) e33-e43; DOI: 10.1542/neo.18-1-e33

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    Diabetes Mellitus in Pregnancy
    Desmond M. Sutton, Christina S. Han, Erika F. Werner
    NeoReviews Jan 2017, 18 (1) e33-e43; DOI: 10.1542/neo.18-1-e33
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    • Article
      • Abstract
      • Education Gaps
      • Objectives
      • Introduction
      • Epidemiology
      • Classification And Pathophysiology Of Diabetes In Pregnancy
      • Impact Of Diabetes In Pregnancy On The Neonate
      • Maternal Monitoring To Limit Neonatal Effects
      • Conclusions
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      • References
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