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American Academy of Pediatrics
Article

Diagnostic Use of C-Reactive Protein (CRP) in Assessment of Neonatal Sepsis

Jörn-Hendrik Weitkamp and Judy L. Aschner
NeoReviews November 2005, 6 (11) e508-e515; DOI: https://doi.org/10.1542/neo.6-11-e508
Jörn-Hendrik Weitkamp
*Division of Neonatology, Department of Pediatrics, Vanderbilt Children’s Hospital, Nashville, Tenn
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Judy L. Aschner
*Division of Neonatology, Department of Pediatrics, Vanderbilt Children’s Hospital, Nashville, Tenn
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Article Information

vol. 6 no. 11 e508-e515
DOI 
https://doi.org/10.1542/neo.6-11-e508

Published By 
American Academy of Pediatrics
Print ISSN 
1526-9906
Online ISSN 
1526-9906
History 
  • Published online November 1, 2005.

Copyright & Usage 
Copyright © 2005 by the American Academy of Pediatrics

Author Information

  1. Jörn-Hendrik Weitkamp, MD*, and
  2. Judy L. Aschner, MD*
  1. *Division of Neonatology, Department of Pediatrics, Vanderbilt Children’s Hospital, Nashville, Tenn
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NeoReviews
Vol. 6, Issue 11
1 Nov 2005
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Diagnostic Use of C-Reactive Protein (CRP) in Assessment of Neonatal Sepsis
Jörn-Hendrik Weitkamp, Judy L. Aschner
NeoReviews Nov 2005, 6 (11) e508-e515; DOI: 10.1542/neo.6-11-e508

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Diagnostic Use of C-Reactive Protein (CRP) in Assessment of Neonatal Sepsis
Jörn-Hendrik Weitkamp, Judy L. Aschner
NeoReviews Nov 2005, 6 (11) e508-e515; DOI: 10.1542/neo.6-11-e508
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  • Table of Contents

Jump to section

  • Article
    • Objectives
    • Introduction
    • The Pursuit of a Diagnostic Sepsis Marker
    • What is CRP?
    • Measuring CRP in Blood
    • Measuring CRP in Cerebrospinal Fluid
    • Factors That Can Influence CRP Concentrations
    • CRP for Assessment of Sepsis in Term Infants
    • Serial CRP Concentrations Versus Single Measurements
    • IL-6 and Procalcitonin Diagnostic Tests
    • Combination of CRP and IL-8
    • Proposed CRP protocol
    • Conclusion
    • Acknowledgments
    • Footnotes
    • Suggested Reading
  • Figures & Data
  • Info & Metrics
  • Comments

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  • Congenital Hyperinsulinism
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Subjects

  • Fetus/Newborn Infant
    • Fetus/Newborn Infant
    • Neonatology

Keywords

  • CBC: complete blood count
  • CRP: C-reactive protein
  • CSF: cerebrospinal fluid
  • IL: interleukin
  • NICU: neonatal intensive care unit
  • ROC: receiver-operator characteristic
  • PCT: procalcitonin
  • VLBW: very low-birthweight
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