RT Journal Article SR Electronic T1 Obesity and Pregnancy JF NeoReviews JO NeoReviews FD American Academy of Pediatrics SP e78 OP e87 DO 10.1542/neo.22-2-e78 VO 22 IS 2 A1 Paredes, Carmen A1 Hsu, Richard C. A1 Tong, Anna A1 Johnson, Jeffery R. YR 2021 UL http://neoreviews.aappublications.org/content/22/2/e78.abstract AB Abbreviations:BMI: body mass indexCI: confidence intervalIOM: Institute of MedicineLGA: large for gestational ageOR: odds ratioRR: relative riskWHO: World Health OrganizationThe worldwide rates of obesity have increased significantly in recent decades. In the United States, more than 50% of pregnant women are overweight or obese. Obese gravid women are more prone to adverse pregnancy outcomes, including gestational diabetes, hypertensive disorders, and cardiovascular diseases. The adverse outcomes extend beyond the pregnant obese woman; offspring of obese women are themselves at increased risk of prematurity, fetal death, injury during birth, and transient respiratory problems and metabolic effects (ie, neonatal hypoglycemia). Furthermore, maternal obesity can predispose their offspring to long-term health problems, potentially generating an intergenerational cycle of obesity and insulin resistance.